Sidney is hibernating in the woods, her whereabouts are unknown to everyone but Dewey. After a number of murders that seem to be related to the Woodsboro case take place on the set of Stab 3, Sid comes to Hollywood to be terrorized, find out more about her mother’s death, and put together the final pieces of the Scream mystery. In the final installment to this trilogy, a murdering spree begins to happen again; this time targeted toward the orginal Woodsboro survivors and those associated with the movie-inside a-movie, Stab 3. Sydney must face the demons of her past to stop the killer(s). While Sidney and her friends visit the Hollywood set of Stab 3, the third film based on the Woodsboro murders, a new Ghostface begins to terrorize them once again.